Student Projects
Ex Vivo Perfusion Machine - Mechanical Design of the Disposable Set
Ex vivo perfusion machines keep organs alive outside the body by driving warm, oxygenated blood through their vessels. They help to address the organ shortage by turning marginal organs into transplantable ones. For mechanical engineering students, these systems show fluid mechanics, heat transfer, and control technology at work under real biological constraints. Pumps, sensors, and feedback loops must hold flow, pressure, and temperature within tight limits. Even small design choices influence organ viability. This thesis is an opportunity for you to have a direct impact on future transplant patients' lives.
Keywords
Mechanical Engineering, CAD, 3D printing, Bachelor's Thesis
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Bachelor Thesis , ETH Zurich (ETHZ)
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Published since: 2025-12-18 , Earliest start: 2026-02-01 , Latest end: 2026-06-01
Organization Research Onder
Hosts Machacek David
Topics Engineering and Technology
Ex Vivo Perfusion Machine - Modelling of Glucose Homeostasis
Ex vivo perfusion machines keep organs alive outside the body by driving warm, oxygenated blood through their vessels. They help to address the organ shortage by turning marginal organs into transplantable ones. For mechanical engineering students, these systems show fluid mechanics, heat transfer, and control technology at work under real biological constraints. Pumps, sensors, and feedback loops must hold flow, pressure, and temperature within tight limits. Even small design choices influence organ viability. This thesis is an opportunity for you to have a direct impact on future transplant patients' lives.
Keywords
Mechanical engineering, Biomedical engineering, Bachelor's thesis, Mathematical modelling
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Bachelor Thesis , ETH Zurich (ETHZ)
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Published since: 2025-12-18 , Earliest start: 2026-02-01 , Latest end: 2026-06-01
Organization Research Onder
Hosts Machacek David
Topics Engineering and Technology
Development of a Fully Automatic Syringe System to Investigate Drug Induced Liver Injury
Drug Induced Liver Injury (DILI) is a serious condition that can arise fom specific drugs, drug combinations, or their metabolites. We aim to improve safety during drug therapy by focusing on patientspecific DILI, by using cells that are taken from individual patients that therefore carry the genetic makeup and immunogenicity of the donor. Exposing these cells to drugs gives information on the tolerance of the patient to the specific drug. However, the cells not only need to be in contact with the drug, but they need flow exposure.
Keywords
Mechanical engineering, Master's thesis, Start-up, Biomedical engineering, Medtech
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Collaboration , Master Thesis , ETH Zurich (ETHZ)
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Published since: 2025-12-18 , Earliest start: 2026-02-01 , Latest end: 2026-11-30
Organization Research Onder
Hosts Machacek David
Topics Medical and Health Sciences , Information, Computing and Communication Sciences , Engineering and Technology
Modelling and Optimal Control of a Turbocharger Gas-Flow Testbench
This master's thesis aims to develop a model-based optimal control strategy to accelerate the measurement process on a turbocharger gas-flow testbench. By modeling the temperature dynamics of the testbench and turbocharger housing, and identifying parameters from existing data, the project will enable faster transitions between operating points. The optimized control strategy will be compared to current methods, and additional focus will be placed on minimizing overall measurement time by optimizing the sequence of test points. The work supports Accelleron's efforts in efficient turbocharger characterization.
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Master Thesis
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Published since: 2025-12-08 , Earliest start: 2025-12-01
Applications limited to ETH Zurich
Organization Research Onder
Hosts Widmer Fabio
Topics Information, Computing and Communication Sciences , Engineering and Technology